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Monobac (Roxithromycin)

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Monobac is indicated for the treatment of the following mild to moderately severe infections in children caused by or likely to be caused by susceptible micro-organisms: acute pharyngitis, acute tonsillitis and impetigo.

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Also known as: Roxithromycin


Monobac is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections. Monobac is derived from erythromycin, containing the same 14-membered lactone ring. However, an N-oxime side chain is attached to the lactone ring. It is also currently undergoing clinical trials for the treatment of male-pattern hair loss.

Monobac is available under several brandnames. Monobac is not available in the United States. Monobac is available in Australia, Israel and New Zealand. Monobac has also been tested to possess antimalarial activity.

Monobac prevents bacteria from growing, by interfering with their protein synthesis. Monobac binds to the subunit 50S of the bacterial ribosome, and thus inhibits the synthesis of peptides. Monobac has similar antimicrobial spectrum as erythromycin, but is more effective against certain gram-negative bacteria, particularly Legionella pneumophila.


Monobac is typically prescribed for a period of 7 to 14 days and patients should take the medication for as long as it has been prescribed to prevent the infection from returning even if they become asymptomatic. Patients should not however, take doses larger than has been prescribed as this can result in an overdose. Overdosing requires immediate medical intervention and may present with symptoms which include abdominal pain, nausea, diarrhea, vomiting, and a general and prolonged feeling of illness.


Symptomatic treatment should be provided as required. There is no specific antidote.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture, light and heat. Do not store in the bathroom. Keep in a tight, light-resistant container. Keep out of the reach of children.

Side effects

The most common side effects associated with Monobac are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Generic Monobac if you are allergic to Generic Monobac components. Try to be careful with Generic Monobac if you're pregnant or you plan to have a baby, or you are a nursing mother. It can be dangerous to stop Generic Monobac taking suddenly.

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