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Leedom (Lansoprazole)

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Leedom is used to treat symptoms of gastroesophageal reflux disease (GERD) and other conditions involving excessive stomach acid. It has few side effects, but it can take up to 4 days to feel the full effect of the medication.

Other names for this medication:
Cyplan, Cytolog, Domaci, Domsin, Heligo, Jpzole, Lancid, Lancidom, Lanex, Langard, Lanip, Lanrid, Lansoprazole, Lansoriv, Lansoz, Lansure, Lansver, Lanzap, Lanzee, Lanzosec, Lasole, Lazis, Leedom, Lesozap, Lezol, Locid, Mesopil, Nazol, Onilan, Prezole, Protogut, Pylokit, Pylomox, Sensicaine, Zapacid

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Also known as: Lansoprazole


Leedom NapraPAC contains a combination of naproxen and lansoprazole. Naproxen is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing substances in the body that cause inflammation, pain, and fever. Lansoprazole is a proton pump inhibitor. It decreases the amount of acid produced in the stomach.

Leedom NapraPAC is used to treat symptoms of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. The lansoprazole in Leedom NapraPAC helps reduce the risk of stomach ulcers in people who may be at risk for them while receiving treatment with an NSAID.


Take Leedom NapraPAC exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Each package of Leedom NapraPAC contains pills for 7 days of treatment (one lansoprazole capsule and two naproxen tablets per day). In most cases, you will take one lansoprazole (Leedom) capsule and one naproxen (Naprosyn) tablet each morning before eating. The second naproxen tablet is then taken 12 hours later, without lansoprazole. Follow your doctor's instructions.

Do not crush, chew, break, or open the lansoprazole capsule. Swallow it whole. Breaking or opening the pill may cause too much of the drug to be released at one time.

To be sure Leedom NapraPAC is not causing harmful effects, your blood may need to be tested often. Your kidney or liver function may also need to be tested. You may also need eye exams if you have any changes in your vision. Visit your doctor regularly.

Leedom NapraPAC can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using Leedom NapraPAC.

Store Leedom NapraPAC at room temperature away from moisture, heat, and light.

Detailed Leedom NapraPAC dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Leedom are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Leedom NapraPAC if you are allergic to lansoprazole (Leedom) or naproxen (Aleve, Anaprox, Naprosyn, and others), or if you have ever had a severe allergic reaction to aspirin or other NSAIDs. Do not use Leedom NapraPAC just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

The naproxen in Leedom NapraPAC may cause life-threatening heart or circulation problems such as heart attack or stroke, especially if you use it long term.

Naproxen may also cause serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and can occur without warning while you are taking Leedom NapraPAC, especially in older adults.

To make sure you can safely take Leedom NapraPAC, tell your doctor if you have any of these other conditions:

liver or kidney disease; heart disease, high blood pressure, fluid retention, or a history of stroke, heart attack, or congestive heart failure; low levels of magnesium in your blood; a bleeding or blood clotting disorder, such as hemophilia; a history of stomach ulcers or bleeding; asthma, or a history of allergic reaction to aspirin, especially aspirin triad syndrome; or if you smoke.

FDA pregnancy category C. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Taking naproxen during the last 3 months of pregnancy may result in birth defects. Do not take Leedom NapraPAC during pregnancy unless your doctor has told you to. Naproxen can pass into breast milk and may harm a nursing baby. You should not breast-feed while taking Leedom NapraPAC.

Leedom NapraPAC pregnancy and breastfeeding warnings (more detail)

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